O'n ikki barmoqli ichak yarasi bo'lgan bemorlarda fizik omillarning morfologik xususiyatlarga ta'siri
Annotatsiya
Tadqiqot ichak disbiyozi bilan og'rigan 57 bemorda o'tkazildi. Ularning 22 nafari ayol va 27 nafari erkak edi. Bemorlarning yoshi 18 yoshdan 65 yoshgacha bo'lgan. Barcha bemorlarga dysbioz tashxisi qo'yilgan. Oshqozon yarasini tekshirish endoskopik, immunoassay fermenti yordamida Helicobacter pylori va mikrobiologik tadqiqot usullari bilan yo'g'on ichak disbiyozi mavjudligi aniqlandi. Bemorlar 3 guruhga bo'lingan: sinusoidal modulyatsiyalangan to'lqinlar terapiyasini olgan 23 bemor, transkranial elektr stimulyatsiya terapiyasini olgan 19 bemor va o'n ikki barmoqli ichak uchburchagi va transkranial elektr stimulyatsiyasiga sinusoidal modulyatsiyalangan to'lqinlar terapiyasini olgan 15 bemor. Nazorat guruhi Helicobacter pylori infektsiyasini davolash bo'yicha Maastricht V/Florence konsensus tavsiyalariga muvofiq standart eradikatsiya terapiyasidan o'tgan bemorlardan (20 bemor) iborat edi. Olingan ma'lumotlar shuni ko'rsatadiki, eradikatsiya terapiyasi sxemasiga jismoniy omillarni kiritish o'n ikki barmoqli ichak shilliq qavatining hujayra tarkibida yanada aniq ijobiy o'zgarishlarga olib keladi, bu yallig'lanish va immunoilflamatuar jarayonlar faolligining pasayishini ko'rsatishi mumkin. Shuningdek, sinusoidal modulyatsiyalangan to'lqinlar va transkranial elektr stimulyatsiyasi bilan terapiya o'zining morfologik samaradorligi bo'yicha yo'nalishi bo'yicha o'xshash standart eradikatsiya terapiyasi sxemalarining ta'siridan sezilarli darajada oshib ketishi isbotlangan. Taxmin qilish mumkinki, Helicobacter pylori infektsiyasini yo'q qilish bo'yicha ko'proq ijobiy dinamika o'n ikki barmoqli ichakning yarali nuqsonlari qirralari bo'ylab neytrofillar va plazmasitik infiltratsiya zichligining pasayishi bilan bog'liq.
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